MyBioSource.com's Mouse Anti-CD3 Antibody is a Mouse monoclonal antibody. It reacts with Human. This antibody has been shown to work in applications such as: Flow Cytometry, and Western Blot.
Description
Information: The human CD3/T cell receptor (TcR) complex is made up of at least five CD3 proteins (gamma, delta, epsilon, h, z) in association with either alpha/beta or gamma/delta proteins of the TcR. The TcR recognizes antigens in association with MHC molecules after which protein chains of the CD3 complex mediate activation signals triggered by TcR antigen binding. CD3 is expressed on greater than 95% of circulating human peripheral T cells. Antibody UCHT1 recognizes the 20 kd episilon chain of the CD3 molecule complex. Antibody UCHT1 will activate T cells expressing CD3epsilon